Ground Truth Data for High Density Silicon Probe Recordings

One way that neurons communicate is via all or nothing physiological events called action potentials. Interestingly, action potentials can be readily and reliably recorded from outside of the neuron by electrodes placed within 100 μm of a neurons cell body. These extracellularly recorded action potentials are fast, typically lasting on the order of just a few ms. It is this fast time-course, and their sharp shape, that has led extracellularly recorded action potentials to be commonly referred to as ‘spikes’.

LeafLabs Awarded NIMH/NIH Phase I STTR Grant

Toward Automated Spike Sorting via Ground Truth Neural Recordings

LeafLabs is excited to announce that the National Institute of Mental Health has awarded us a Phase I Small Business Technology Transfer grant (1R41MH116752-01), amounting to $438k over 12 months. The proposed research will use multi-modal recordings of neuronal activity to generate a corpus of ground truth data for the validation of spike sorting algorithms. This grant will fund a collaboration between LeafLabs and Ed Boyden at MIT.